Special Viral Pathogens Journal [SVPJ]




Seroprevalence of Hepatitis (B and C) viruses among apparently healthy Adults in Ekpoma, Edo State, Nigeria

*1Babatope IO, 1Inyang NJ, 2Imhanrenezor K, 1Aghahowa A.

 Departments of: 1Medical Laboratory Sciences and 2Microbiology, Ambrose Alli University, Ekpoma, Edo State, Nigeria.

Special Viral Pathogens Journal (SVPJ) 2015; Vol 1, No 1: p 00015-00020

Correspondence: *E-mail: babatope_olaniyi@yahoo.com  Tel: +2348035637399

How to cite this article:

Babatope IO, Inyang NJ, Imhanrenezor K, Aghahowa A. Seroprevalence of Hepatitis B and C viruses  among apparently healthy adults in Ekpoma, Edo State, Nigeria. Special Viral Pathogens Journal (SVPJ) 2015; Vol 1, No 1: p 0015-0020


Background: Infections with the hepatitis B virus (HBV) and/or the hepatitis C virus (HCV) are public health problems, which are highly endemic in the sub-Saharan Africa countries where Nigeria is located. Early and accurate diagnosis of co-infections with mono- and/or polymicrobial agents, in resource limited settings remains the key to effective interventions. Objective: This study was carried out to determine the seroprevalence of hepatitis B and hepatitis C viruses among apparently healthy individuals in Ekpoma, Edo State, Nigeria. Materials and Methods: In this cross-sectional laboratory based study, three hundred blood samples were aseptically collected from apparently healthy individuals randomly selected from Ekpoma community. Participants were screened for hepatitis B surface antigen and anti HCV antibody using standard methods. Ethical clearance and participant’s informed consent were sought and obtained from appropriate authorities and concerned participants. All data generated in this investigation were analyzed for statistical relevance using Pearson’s Chi square software. Results: Of the 300 samples screened, 8.3% were seropositive for hepatitis B surface antigen while 3% was seropositive for anti-HCV antibody. The sex related prevalences of 4.7% in females and 3.6% in males were obtained for HBV while HCV recorded 2.3% for females and 0.7% for males. HBV and HCV infections were not significantly (p<0.05) associated with the sex of participants. Age related prevalence for HBsAg were 4%, 3% and 1.3% among the age groups 19-29, 30-39 and 40 and above years respectively while 1%, 1.3% and 0.7% prevalence rates of anti-HCV were observed  among the age groups (19-29, 30-39, 40 and above)years respectively. Conclusion: The observed sero-prevalence of HBV and HCV among apparently healthy individuals in Ekpoma emphasizes the significance of early detection of disease agents in prevention and effective management of disease outbreaks especially in resource limited settings.