Special Pathogens Research Network [Spparenet] Ltd

Abstract

Special Bacterial Pathogens Journal (SBPJ) 2015; Vol 1, No 1: p 00010-0015. Copyright © Special Pathogens Research Network Limited, Uganda, All Rights Reserved

Prevalence and susceptibility pattern of bacterial urinary tract infections among pregnant HIV positive women in Gucha sub county, Kenya

 1Maniga N J, 2Mogaka G, 3Nyambane L and 1Eilu E

 1. Department of Microbiology and Immunology, Kampala International University-Western Campus, P.O BOX 71, Bushenyi, Uganda. 2. Migori Referral Hospital, P.O Box 5 Migori.Kenya, 3. Kenyenya polytechnic P.O BOX 68 Kenyenya, Kenya,

How to cite this article

Maniga NJ, Mogaka G, Nyambane L and Eilu E.  Prevalence and susceptibility pattern of bacterial Urinary Tract Infections among pregnant HIV positive women in Gucha sub county, Kenya (SBPJ) 2015; Vol 1, No 1: p 00010-0015.

ABSTRACT

Back ground: The Urinary tract infection are the most frequent infection in women and complications with other diseases like HIV/AIDS, diabetes makes its management a top public health concern especially in resource limited setting. Objectives: The main aim of this present study was to determine the prevalence of bacterial UTI among HIV and access the ant-microbial susceptibility of the isolated Bacteria uropathogens in HIV positive pregnant patients in Gucha Sub County District. Materials and Methods: A prospective cross-sectional study carried out at Gucha sub county District HIV/AIDS clinic. Mid-stream urine samples were collected from consenting 196 females, who were clinically diagnosed with UTI by the attending Physicians. Standard Microbiological methods were used in the isolation and characterization of bacterial uro-pathogens. Clinical Laboratory Standards Institutes modifications of Kirby-Bauer disc diffusion technique were adopted. The data was presented as mean ± standard deviation (SD) and compared with student t-test. Results: Out of 200 mid-stream urine samples, 35 pure significant bacterial growth (105 colony forming units/ml of urine) were isolated and these included Escherichia coli, 15(43%), Staphylococcus aureus, 7 (20%) S.saprophyticus 5(14%) Enterococci species, 4(11%) and Klebsiella, 4(11%). The uropathogens isolated were more sensitive to Gentamicin, 32(21%) followed with ciproflaxcin, 26(17%), Nitrofurantoin, 20(13%), Erytromcin, 12(12%) and Nilidixic acid, 17(11%) respectively. Conclusion: Escherichia coli were the most dominant bacteria occurring in the pregnant HIV Patients at Gucha Sub County District. Consequently Gentamycin should be considered a drug of choice for empirical treatment of UTI in pregnant HIV/AIDS females.

Keywords: UTI, pregnant women, Antibacterial, HIV, Seropositive females

 *Corresponding author: Josephat Maniga Nyabayo, Department of Microbiology and Immunology, Faculty of Biomedical Sciences, Kampala International University-Western Campus, P.O BOX 71, Bushenyi, Uganda, Tel: +256701238130; E-mail: josnyabayo@yahoo.com